Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 2/20 | 0.34 |
| ▸ | SUZ12 | Q15022 | 2/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | SOD1 | P00441 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23109717 | 0.85 | HPGD (0.33) | EEDSUZ12EZH2HPGDP2RX7 | |
| SCHEMBL23109716 | 0.85 | HPGD (0.33) | EEDSUZ12EZH2HPGDP2RX7 | |
| SCHEMBL23109718 | 0.85 | HPGD (0.33) | EEDSUZ12EZH2HPGDP2RX7 | |
| SCHEMBL23109719 | 0.82 | EED (0.36) | EEDSUZ12EZH2HIF1AEPAS1 | |
| SCHEMBL23109830 | 0.81 | EED (0.50) | EEDSUZ12EZH2HIF1AEPAS1 | |
| SCHEMBL23109720 | 0.79 | EED (0.34) | EEDSUZ12EZH2HIF1AEPAS1 | |
| SCHEMBL23109724 | 0.78 | EED (0.34) | EEDSUZ12EZH2HIF1AEPAS1 | |
| SCHEMBL21332605 | 0.75 | KDM4C (0.43) | TACR1TACR3SOD1 | |
| SCHEMBL21332603 | 0.75 | KDM4C (0.43) | TACR1TACR3SOD1 | |
| SCHEMBL21344576 | 0.75 | KDM4C (0.43) | TACR1TACR3SOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021047616-A1 | OXYNITRIDE HETEROCYCLIC HEPTANE-BASED SPIRO COMPOUND, INTERMEDIATE AND PREPARATION METHOD THEREFOR | 苏州亚盛药业有限公司 | 2021-03-18 | — | — | WO | disclosed |