Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28911951 | 0.95 | IRAK4 (0.72) | IRAK4 | |
| SCHEMBL23110402 | 0.90 | IRAK4 (0.66) | IRAK4 | |
| SCHEMBL23110662 | 0.88 | IRAK4 (1.00) | IRAK4 | |
| Trifluoroacetic Acid SCHEMBL28559266 | 0.85 | IRAK4 (0.61) | IRAK4 | |
| SCHEMBL23110405 | 0.84 | IRAK4 (0.78) | IRAK4 | |
| SCHEMBL23110403 | 0.80 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL23110643 | 0.80 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL28555183 | 0.78 | IRAK4 (0.61) | IRAK4 | |
| SCHEMBL23093796 | 0.78 | IRAK4 (0.86) | IRAK4 | |
| SCHEMBL23110472 | 0.78 | IRAK4 (1.00) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021047677-A1 | IRAK4 KINASE INHIBITOR AND PREPARATION THEREOF AND USE THEREOF | 中国科学院上海药物研究所 | 2021-03-18 | — | — | WO | disclosed |