Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23374138 | 0.78 | KDM4E (0.30) | — | |
| SCHEMBL10149500 | 0.78 | KDM4E (0.30) | — | |
| SCHEMBL23171490 | 0.68 | — | — | |
| SCHEMBL9943069 | 0.67 | — | — | |
| SCHEMBL13884405 | 0.67 | KDM4E (0.33) | EPHX1 | |
| SCHEMBL13877874 | 0.67 | KDM4E (0.33) | EPHX1 | |
| SCHEMBL13877824 | 0.67 | KDM4E (0.33) | EPHX1 | |
| SCHEMBL21082361 | 0.65 | GLB1 (0.31) | — | |
| SCHEMBL12899666 | 0.65 | GAA (0.31) | — | |
| SCHEMBL10967639 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021047677-A1 | IRAK4 KINASE INHIBITOR AND PREPARATION THEREOF AND USE THEREOF | 中国科学院上海药物研究所 | 2021-03-18 | — | — | WO | disclosed |