Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21840495 | 0.90 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL23110458 | 0.90 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL23110647 | 0.89 | IRAK4 (0.83) | IRAK4 | |
| SCHEMBL21840546 | 0.89 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL21840512 | 0.85 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL21840553 | 0.85 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL21840523 | 0.84 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL21840528 | 0.83 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL21840511 | 0.83 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL21840557 | 0.82 | IRAK4 (1.00) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021047677-A1 | IRAK4 KINASE INHIBITOR AND PREPARATION THEREOF AND USE THEREOF | 中国科学院上海药物研究所 | 2021-03-18 | — | — | WO | disclosed |
| CN-112480101-A | IRAK4 kinase inhibitor and preparation and application thereof | 中国科学院上海药物研究所 | 2021-03-12 | — | — | CN | disclosed |