⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26276037 | 1.00 | — | — | |
| SCHEMBL9800287 | 1.00 | — | — | |
| SCHEMBL17366317 | 0.77 | — | — | |
| SCHEMBL353917 | 0.76 | — | — | |
| SCHEMBL7901387 | 0.76 | — | — | |
| SCHEMBL8536133 | 0.76 | — | — | |
| SCHEMBL18358128 | 0.74 | — | — | |
| SCHEMBL583977 | 0.74 | — | — | |
| SCHEMBL7914616 | 0.74 | — | — | |
| SCHEMBL587983 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475262-B1 | BICYCLIC IMIDAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF RENAL DISEASE, CARDIOVASCULAR DISEASES AND FIBROTIC DISORDERS | BOEHRINGER INGELHEIM INT (DE) | 2021-03-24 | — | — | EP | disclosed |