Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 9/20 | 0.51 |
| ▸ | CTSG | P08311 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2311390 | 1.00 | CMA1 (0.51) | CMA1CTSGMEN1KMT2AALDH1A1 | |
| SCHEMBL2808902 | 0.85 | CMA1 (0.49) | CMA1CTSGMEN1KMT2AALDH1A1 | |
| SCHEMBL2808906 | 0.85 | CMA1 (0.49) | CMA1CTSGMEN1KMT2AALDH1A1 | |
| SCHEMBL2310378 | 0.83 | CMA1 (0.55) | CMA1CTSGGAA | |
| SCHEMBL2311012 | 0.83 | CMA1 (0.55) | CMA1CTSGGAA | |
| SCHEMBL2311393 | 0.81 | CMA1 (0.52) | CMA1CTSGMEN1KMT2AALDH1A1 | |
| SCHEMBL2309949 | 0.80 | CMA1 (0.55) | CMA1CTSGMEN1KMT2A | |
| SCHEMBL2314721 | 0.79 | CMA1 (0.49) | CMA1CTSGMEN1KMT2AALDH1A1 | |
| SCHEMBL2314717 | 0.79 | CMA1 (0.49) | CMA1CTSGMEN1KMT2AALDH1A1 | |
| SCHEMBL2311861 | 0.78 | CMA1 (0.55) | CMA1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152674-B1 | BENZIMIDAZOLONE CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2011-08-03 | — | — | EP | disclosed |