SCHEMBL23114367

SCHEMBL23114367

Cc1ccc(-c2cnc3cc(C)ccc3n2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
RAB9A P51151 2/20 0.54
PDGFRB P09619 2/20 0.54
KDR P35968 1/20 0.54
FLT3 P36888 1/20 0.54
TLR9 Q9NR96 1/20 0.51
BCHE P06276 1/20 0.47
NQO2 P16083 1/20 0.47
MAPT P10636 2/20 0.46
ALDH1A1 P00352 2/20 0.46
GLA P06280 1/20 0.46
GAA P10253 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
KDM4E B2RXH2 2/20 0.45
PDGFRA P16234 1/20 0.45
APP P05067 5/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18806855 0.98 NPC1 (0.53) NPC1SMN1; SMN2RAB9APDGFRBKDR
SCHEMBL14261863 0.98 NPC1 (0.56) NPC1SMN1; SMN2RAB9APDGFRBKDR
SCHEMBL16687607 0.89 NPC1 (0.70) NPC1SMN1; SMN2RAB9APDGFRBKDR
SCHEMBL29184272 0.85 NPC1 (0.74) NPC1SMN1; SMN2RAB9APDGFRBKDR
SCHEMBL30846532 0.85 NPC1 (0.74) NPC1SMN1; SMN2RAB9APDGFRBKDR
SCHEMBL17149187 0.84 NPC1 (0.51) NPC1SMN1; SMN2RAB9APDGFRBKDR
SCHEMBL9453978 0.83 NPC1 (0.68) NPC1SMN1; SMN2RAB9APDGFRBKDR
SCHEMBL13541764 0.82 NPC1 (0.70) NPC1SMN1; SMN2RAB9APDGFRBKDR
SCHEMBL29184278 0.82 SMN1; SMN2 (0.56) NPC1SMN1; SMN2RAB9APDGFRBKDR
SCHEMBL29184277 0.82 NPC1 (0.56) NPC1SMN1; SMN2RAB9APDGFRBKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11034797-B2 Polyimide precursor composition, use thereof and polyimide made therefrom ETERNAL MATERIALS CO., LTD. (TW) 2021-06-15 US disclosed
US-20210079161-A1 POLYIMIDE PRECURSOR COMPOSITION, USE THEREOF AND POLYIMIDE MADE THEREFROM ETERNAL MATERIALS CO., LTD. (TW) 2021-03-18 US disclosed