Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.83 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.66 |
| ▸ | GSK3B | P49841 | 6/20 | 0.56 |
| ▸ | GSK3A | P49840 | 5/20 | 0.56 |
| ▸ | AURKA | O14965 | 3/20 | 0.56 |
| ▸ | PTK2 | Q05397 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.49 |
| ▸ | CHUK | O15111 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032124 | 0.91 | PLK1 (1.00) | PLK1MAPTPTK2BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3808883 | 0.90 | PLK1 (0.98) | PLK1MAPTPTK2BMEN1KMT2A | |
| SCHEMBL4025594 | 0.84 | PLK1 (0.84) | PLK1MAPTPTK2BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3810870 | 0.83 | PLK1 (0.82) | PLK1MAPTPTK2BMEN1KMT2A | |
| SCHEMBL13866466 | 0.83 | PLK1 (0.81) | PLK1MAPTPTK2BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3814491 | 0.82 | PLK1 (0.80) | PLK1MAPTPTK2BMEN1KMT2A | |
| SCHEMBL5408359 | 0.81 | MAPT (0.86) | PLK1MAPTPTK2BMEN1KMT2A | |
| SCHEMBL4031609 | 0.80 | MAPT (0.70) | PLK1MAPTPTK2BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3814985 | 0.79 | MAPT (0.69) | PLK1MAPTPTK2BMEN1KMT2A | |
| SCHEMBL13866473 | 0.78 | PLK1 (0.72) | PLK1MAPTPTK2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021050917-A1 | PHOSPHOLIPID ETHER CONJUGATES AS CANCER-TARGETING DRUG VEHICLES | CELLECTAR BIOSCIENCES, INC. (US) | 2021-03-18 | — | — | WO | disclosed |