Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120402 | 1.00 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KBDOT1L | |
| SCHEMBL23120692 | 0.86 | DOT1L (0.41) | PI4KAPI4K2BPI4K2API4KBDOT1L | |
| SCHEMBL23120696 | 0.86 | DOT1L (0.41) | PI4KAPI4K2BPI4K2API4KBDOT1L | |
| SCHEMBL23120523 | 0.85 | DOT1L (0.41) | PI4KAPI4K2BPI4K2API4KBDOT1L | |
| SCHEMBL23120518 | 0.85 | DOT1L (0.42) | PI4KAPI4K2BPI4K2API4KBDOT1L | |
| SCHEMBL23120521 | 0.85 | DOT1L (0.41) | PI4KAPI4K2BPI4K2API4KBDOT1L | |
| SCHEMBL23120520 | 0.85 | DOT1L (0.42) | PI4KAPI4K2BPI4K2API4KBDOT1L | |
| SCHEMBL26530697 | 0.85 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBDOT1L | |
| SCHEMBL24450651 | 0.85 | PI4KA (0.51) | PI4KAPI4K2BPI4K2API4KBDOT1L | |
| SCHEMBL29695827 | 0.85 | PI4KA (0.51) | PI4KAPI4K2BPI4K2API4KBDOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021053158-A1 | NOVEL HISTONE METHYLTRANSFERASE INHIBITORS | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2021-03-25 | — | — | WO | disclosed |