Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29871781 | 1.00 | CTPS1 (0.78) | CTPS1 | |
| SCHEMBL22749250 | 0.93 | CTPS1 (0.84) | CTPS1 | |
| SCHEMBL22736740 | 0.90 | CTPS1 (0.84) | CTPS1 | |
| SCHEMBL23121306 | 0.89 | CTPS1 (0.77) | CTPS1 | |
| SCHEMBL22758517 | 0.89 | CTPS1 (0.79) | CTPS1 | |
| SCHEMBL29508490 | 0.89 | CTPS1 (0.79) | CTPS1 | |
| SCHEMBL24895705 | 0.89 | CTPS1 (0.78) | CTPS1 | |
| SCHEMBL24849352 | 0.89 | CTPS1 (0.78) | CTPS1 | |
| SCHEMBL22749224 | 0.89 | CTPS1 (0.78) | CTPS1 | |
| SCHEMBL29369234 | 0.89 | CTPS1 (0.78) | CTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041723-A2 | SULFONAMIDE DERIVATIVES AS CTPS1 INHIBITORS | Step Pharma S.A.S. (FR) | 2022-08-17 | — | — | EP | disclosed |
| WO-2021053402-A2 | COMPOUNDS | STEP PHARMA S.A.S. (FR) | 2021-03-25 | — | — | WO | disclosed |