SCHEMBL23124875

SCHEMBL23124875

O=C(O)CCc1cc(Cl)cc(Cl)c1C(F)(F)F

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR17 Q13304 4/20 0.49
FFAR4 Q5NUL3 5/20 0.43
FFAR1 O14842 4/20 0.43
NPSR1 Q6W5P4 1/20 0.41
FBP1 P09467 1/20 0.40
PLAU P00749 1/20 0.40
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23124826 0.80 CYP4F2 (0.43)
SCHEMBL7344359 0.76 GPR17 (0.54) GPR17FFAR4FFAR1NPSR1FBP1
SCHEMBL7346626 0.75 GPR17 (0.53) GPR17FFAR4FFAR1NPSR1FBP1
Trifluoroacetic Acid SCHEMBL34475873 0.74 FFAR1 (0.43) GPR17FFAR4FFAR1NPSR1PLAU
SCHEMBL1590066 0.71 GPR17 (0.57) GPR17FFAR4FFAR1NPSR1FBP1
SCHEMBL31750436 0.71 FFAR1 (0.54) FFAR4FFAR1
SCHEMBL4007916 0.71 FFAR1 (0.58) FFAR4FFAR1RXRARXRBRXRG
SCHEMBL15532382 0.71 POLQ (0.52) FFAR4FFAR1NPSR1RXRARXRB
SCHEMBL30567601 0.70 PDPK1 (0.59) GPR17FFAR1
SCHEMBL586345 0.70 PDPK1 (0.59) GPR17FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4031530-A1 META-DIAMIDE INSECTICIDES FMC CORPORATION (US) 2022-07-27 EP disclosed
WO-2021055905-A1 META-DIAMIDE INSECTICIDES FMC CORPORATION (US) 2021-03-25 WO disclosed