Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ECE1 | P42892 | 5/20 | 0.59 |
| ▸ | ACE | P12821 | 2/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | MMP8 | P22894 | 2/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | CTSC | P53634 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915265 | 0.92 | ECE1 (0.63) | KDM4EMAPTPOLBAPAF1RECQL | |
| SCHEMBL24899442 | 0.92 | ECE1 (0.63) | KDM4EMAPTPOLBAPAF1RECQL | |
| SCHEMBL19138365 | 0.90 | KDM4E (0.58) | KDM4EMAPTPOLBAPAF1RECQL | |
| SCHEMBL17469322 | 0.90 | KDM4E (0.58) | KDM4EMAPTPOLBAPAF1RECQL | |
| SCHEMBL19138342 | 0.87 | ECE1 (0.58) | KDM4EMAPTPOLBAPAF1RECQL | |
| SCHEMBL19138339 | 0.87 | ECE1 (0.58) | KDM4EMAPTPOLBAPAF1RECQL | |
| SCHEMBL7854107 | 0.84 | KDM4E (0.70) | KDM4EMAPTPOLBAPAF1RECQL | |
| SCHEMBL26168931 | 0.83 | POLB (0.62) | KDM4EMAPTPOLBAPAF1RECQL | |
| SCHEMBL16656724 | 0.83 | ECE1 (0.67) | KDM4EMAPTPOLBAPAF1RECQL | |
| SCHEMBL8266826 | 0.82 | POLB (0.76) | KDM4EMAPTPOLBAPAF1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3171941-B1 | N-METHYL-D-ASPARTATE RECEPTOR MODULATORS AND METHODS OF MAKING AND USING SAME | NAUREX INC (US) | 2021-03-24 | — | — | EP | disclosed |