Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.56 |
| ▸ | AR | P10275 | 7/20 | 0.56 |
| ▸ | ITK | Q08881 | 2/20 | 0.47 |
| ▸ | BTK | Q06187 | 4/20 | 0.46 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22661501 | 0.93 | CRBN (0.49) | CRBNARITKBTKIRAK1 | |
| SCHEMBL23128868 | 0.91 | CRBN (0.56) | CRBNARITKBTKIRAK1 | |
| SCHEMBL25901300 | 0.90 | CRBN (0.55) | CRBNARBTKIRAK1IRAK4 | |
| SCHEMBL22661294 | 0.89 | CRBN (0.52) | CRBNAR | |
| SCHEMBL23129212 | 0.89 | CRBN (0.60) | CRBNARITKBTKIRAK1 | |
| SCHEMBL23129204 | 0.88 | CRBN (0.69) | CRBNARITKBTKIRAK1 | |
| SCHEMBL25900211 | 0.88 | CRBN (0.69) | CRBNARITKBTKIRAK1 | |
| SCHEMBL29597385 | 0.86 | CRBN (0.55) | CRBNARITKBTKIRAK1 | |
| SCHEMBL23129276 | 0.86 | CRBN (0.60) | CRBNARITKBTKIRAK1 | |
| SCHEMBL29058484 | 0.85 | CRBN (0.54) | CRBNARITKBTKIRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3795570-A1 | SUBSTITUTED QUINOLINE-8-CARBONITRILE DERIVATIVES HAVING ANDROGEN RECEPTOR DEGRADATION ACTIVITY AND USES THEREOF | Accutar Biotechnology Inc. (US) | 2021-03-24 | — | — | EP | disclosed |