Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.67 |
| ▸ | BRD9 | Q9H8M2 | 11/20 | 0.67 |
| ▸ | BRD2 | P25440 | 3/20 | 0.53 |
| ▸ | BRD7 | Q9NPI1 | 3/20 | 0.53 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23121920 | 0.85 | BRD4 (0.62) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL23134772 | 0.81 | BRD4 (0.51) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL19869744 | 0.81 | BRD9 (1.00) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL23134715 | 0.79 | BRD9 (0.49) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL23134730 | 0.78 | BRD4 (0.67) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL23134702 | 0.78 | BRD4 (0.65) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL23134699 | 0.78 | BRD4 (0.68) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL19869726 | 0.77 | BRD4 (0.65) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL19869734 | 0.77 | MAPT (0.57) | BRD4BRD9BRD2BRD7 | |
| SCHEMBL24556425 | 0.76 | BRD4 (0.52) | BRD4BRD9BRD2BRD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021055295-A1 | BRD9 BIFUNCTIONAL DEGRADERS AND THEIR METHODS OF USE | NOVARTIS AG (CH) | 2021-03-25 | — | — | WO | disclosed |