Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEU1 | Q99519 | 14/20 | 0.51 |
| ▸ | NEU2 | Q9Y3R4 | 12/20 | 0.51 |
| ▸ | NEU4 | Q8WWR8 | 7/20 | 0.51 |
| ▸ | NEU3 | Q9UQ49 | 7/20 | 0.51 |
| ▸ | MANBA | O00462 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15966479 | 0.80 | NEU1 (0.45) | NEU1NEU2NEU4NEU3 | |
| SCHEMBL21695642 | 0.78 | NEU1 (0.46) | NEU1NEU2NEU4NEU3 | |
| SCHEMBL24437430 | 0.73 | NEU1 (0.42) | NEU1NEU2NEU4NEU3 | |
| SCHEMBL11962046 | 0.73 | NEU1 (0.67) | NEU1NEU2NEU4NEU3 | |
| SCHEMBL10024193 | 0.73 | NEU1 (0.67) | NEU1NEU2NEU4NEU3 | |
| SCHEMBL13191002 | 0.73 | NEU2 (0.63) | NEU1NEU2NEU4NEU3 | |
| SCHEMBL15119388 | 0.73 | NEU1 (0.67) | NEU1NEU2NEU4NEU3 | |
| SCHEMBL22111639 | 0.73 | NEU2 (0.63) | NEU1NEU2NEU4NEU3 | |
| SCHEMBL15368637 | 0.73 | NEU2 (0.63) | NEU1NEU2NEU4NEU3 | |
| SCHEMBL20620266 | 0.73 | NEU2 (0.42) | NEU1NEU2NEU4NEU3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021055753-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF CMP-SUGAR SYNTHETASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-03-25 | — | — | WO | disclosed |