Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 20/20 | 0.58 |
| ▸ | CTSG | P08311 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2315118 | 0.92 | CMA1 (0.62) | CMA1CTSG | |
| SCHEMBL2357589 | 0.92 | CMA1 (0.62) | CMA1CTSG | |
| SCHEMBL8101035 | 0.90 | CMA1 (0.64) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL2309191 | 0.86 | CMA1 (0.75) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL2309639 | 0.86 | CMA1 (0.75) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL2314595 | 0.86 | CMA1 (0.75) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL2313564 | 0.85 | CMA1 (0.60) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL2313766 | 0.85 | CMA1 (0.56) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL2312683 | 0.85 | CMA1 (0.58) | CMA1CTSGHTR1DOPRK1 | |
| SCHEMBL2311491 | 0.84 | CMA1 (0.63) | CMA1CTSGHTR1DOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152674-B1 | BENZIMIDAZOLONE CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2011-08-03 | — | — | EP | disclosed |