Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19534592 | 0.82 | SRD5A1 (0.31) | — | |
| SCHEMBL24771285 | 0.82 | SRD5A1 (0.31) | — | |
| SCHEMBL31642721 | 0.81 | HTR2A (0.32) | HTR2AHTR2CKDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL29336269 | 0.81 | MAPK1 (0.31) | HTR2AHTR2CHTTHTR2BMAPK1 | |
| SCHEMBL3459720 | 0.76 | CYP11B1 (0.38) | HTR2AHTR2C | |
| SCHEMBL326748 | 0.76 | CYP11B1 (0.38) | HTR2AHTR2C | |
| SCHEMBL8614271 | 0.76 | CYP11B1 (0.38) | HTR2AHTR2C | |
| SCHEMBL23135936 | 0.76 | HTR2A (0.31) | HTR2AHTR2C | |
| SCHEMBL27539332 | 0.76 | HTR1D (0.35) | HTR2AHTR2CHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL8614165 | 0.74 | CYP11B1 (0.37) | HTR2AHTR2CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021055376-A1 | IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2021-03-25 | — | — | WO | disclosed |