Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | F7 | P08709 | 4/20 | 0.49 |
| ▸ | F3 | P13726 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | FABP3 | P05413 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22224064 | 1.00 | EPHX2 (0.54) | EPHX2CNR1ALDH1A1F7F3 | |
| SCHEMBL18202081 | 1.00 | EPHX2 (0.54) | EPHX2CNR1ALDH1A1F7F3 | |
| SCHEMBL25672032 | 1.00 | EPHX2 (0.54) | EPHX2CNR1ALDH1A1F7F3 | |
| SCHEMBL27347894 | 1.00 | EPHX2 (0.54) | EPHX2CNR1ALDH1A1F7F3 | |
| SCHEMBL18202080 | 1.00 | EPHX2 (0.54) | EPHX2CNR1ALDH1A1F7F3 | |
| SCHEMBL24411341 | 1.00 | EPHX2 (0.54) | EPHX2CNR1ALDH1A1F7F3 | |
| SCHEMBL22224065 | 1.00 | EPHX2 (0.54) | EPHX2CNR1ALDH1A1F7F3 | |
| SCHEMBL21938252 | 1.00 | EPHX2 (0.54) | EPHX2CNR1ALDH1A1F7F3 | |
| SCHEMBL24856813 | 0.98 | EPHX2 (0.52) | EPHX2CNR1ALDH1A1F7F3 | |
| SCHEMBL25672100 | 0.98 | EPHX2 (0.52) | EPHX2CNR1ALDH1A1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021055609-A1 | MRNA ENCODING ENGINEERED CFTR | TRANSLATE BIO, INC. (US) | 2021-03-25 | — | — | WO | disclosed |