Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 15/20 | 0.42 |
| ▸ | SELP | P16109 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314211 | 0.94 | TLR4 (0.44) | TLR4SELPPTPN1 | |
| SCHEMBL2310785 | 0.93 | TLR4 (0.45) | TLR4SELP | |
| SCHEMBL2313871 | 0.92 | TLR4 (0.41) | TLR4SELPNT5E | |
| SCHEMBL2313867 | 0.87 | TLR4 (0.39) | TLR4SELP | |
| SCHEMBL2311290 | 0.86 | TLR4 (0.45) | TLR4SELP | |
| SCHEMBL9625168 | 0.84 | TLR4 (0.46) | TLR4 | |
| SCHEMBL9786319 | 0.84 | TLR4 (0.44) | TLR4 | |
| SCHEMBL9786324 | 0.84 | TLR4 (0.44) | TLR4 | |
| SCHEMBL2314104 | 0.83 | TLR4 (0.45) | TLR4SELPPTPN1 | |
| SCHEMBL2312471 | 0.83 | TLR4 (0.45) | TLR4SELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232168-B1 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | ONCOTHYREON INC (US) | 2011-08-03 | — | — | EP | disclosed |
| EP-1232168-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001036433-A2 | SYNTHETIC LIPID-A ANALOGS AND USES THEREOF | BIOMIRA, INC. (CA) | 2001-05-25 | — | — | WO | disclosed |