Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL719293 | 0.97 | TSHR (0.35) | TSHRALDH1A1THRB | |
| SCHEMBL3922293 | 0.82 | TSHR (0.37) | TSHRALDH1A1THRB | |
| SCHEMBL23494164 | 0.79 | TSHR (0.37) | TSHRALDH1A1THRB | |
| SCHEMBL5203855 | 0.79 | TSHR (0.41) | TSHRALDH1A1THRB | |
| SCHEMBL27278549 | 0.78 | TSHR (0.39) | TSHRALDH1A1THRB | |
| SCHEMBL23494391 | 0.78 | TSHR (0.39) | TSHRALDH1A1THRB | |
| SCHEMBL28820021 | 0.78 | TSHR (0.32) | TSHRTHRB | |
| Ammonia Solution, Strong SCHEMBL719292 | 0.77 | TSHR (0.36) | TSHRALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL3826580 | 0.77 | TSHR (0.40) | TSHRALDH1A1THRB | |
| SCHEMBL6683823 | 0.77 | TSHR (0.36) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2348831-A2 | ANTIMICROBIAL COMPOSITIONS | Ndsu Research Foundation (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010042935-A2 | ANTIMICROBIAL COMPOSITIONS | NDSU RESEARCH FOUNDATION (US) | 2010-04-15 | — | — | WO | disclosed |
| EP-1005324-B1 | COMPOSITIONS FOR DELIVERY OF BIOLOGICAL AGENTS AND METHODS FOR THE PREPARATION THEREOF | UNIV NEBRASKA (US) | 2005-03-30 | — | — | EP | disclosed |