Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.61 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23153897 | 0.90 | EGFR (0.71) | EGFR | |
| SCHEMBL23154193 | 0.87 | EGFR (0.62) | EGFR | |
| SCHEMBL22025902 | 0.83 | EGFR (0.81) | EGFR | |
| SCHEMBL23154097 | 0.83 | EGFR (0.69) | EGFRINSRIGF1RALK | |
| SCHEMBL22804205 | 0.83 | EGFR (0.73) | EGFRINSRIGF1RALK | |
| SCHEMBL23759753 | 0.82 | EGFR (0.66) | EGFR | |
| SCHEMBL28531005 | 0.82 | EGFR (0.69) | EGFRINSRIGF1RALK | |
| SCHEMBL23153765 | 0.81 | EGFR (0.63) | EGFRINSRIGF1RALK | |
| SCHEMBL24179126 | 0.81 | EGFR (0.68) | EGFRINSRIGF1RALK | |
| SCHEMBL23154142 | 0.81 | EGFR (0.63) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021057882-A1 | EGFR INHIBITOR, COMPOSITION AND PREPARATION METHOD THEREFOR | 贝达药业股份有限公司 | 2021-04-01 | — | — | WO | disclosed |