SCHEMBL23157168

CC(C)(CCC(=O)OC(c1ccccc1)(c1ccc(C2CCCCCCC2)cc1)c1ccccc1Cl)c1ccc(C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)N2CCCCC2)cc1

nearest known ligand 0.39

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	PTPN1	P18031	2/20	0.36

▸	MDM4	O15151	1/20	0.36

▸	TP53	P04637	1/20	0.36

▸	KMT2A	Q03164	3/20	0.36

▸	MEN1	O00255	1/20	0.35

▸	ALDH1A1	P00352	1/20	0.35

▸	MC4R	P32245	2/20	0.34

▸	MC5R	P33032	1/20	0.34

▸	MC3R	P41968	1/20	0.34

▸	MC1R	Q01726	1/20	0.34

▸	CCR1	P32246	3/20	0.34

▸	MAPK1	P28482	1/20	0.34

▸	P2RX7	Q99572	1/20	0.33

▸	HRH2	P25021	1/20	0.33

▸	HRH1	P35367	1/20	0.33

▸	PABPC1	P11940	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23056555	0.90	PTPN1 (0.35)	PTPN1MDM4TP53KMT2AMEN1
SCHEMBL23157160	0.90	PTPN1 (0.35)	PTPN1MDM4TP53KMT2AMEN1
SCHEMBL23056392	0.90	PTPN1 (0.34)	PTPN1MDM4TP53KMT2AMEN1
SCHEMBL23056441	0.90	PTPN1 (0.34)	PTPN1MDM4TP53KMT2AMEN1
SCHEMBL24414034	0.87	MDM4 (0.38)	MDM4TP53CCR1
SCHEMBL24414066	0.87	MDM4 (0.38)	MDM4TP53CCR1
SCHEMBL24828833	0.87	MDM4 (0.38)	MDM4TP53CCR1
SCHEMBL24965995	0.87	MDM4 (0.38)	MDM4TP53CCR1
SCHEMBL24965903	0.87	MDM4 (0.38)	MDM4TP53CCR1
SCHEMBL21950768	0.87	MDM4 (0.38)	MDM4TP53CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2813512-B1	PEPTIDE-COMPOUND CYCLIZATION METHOD	CHUGAI PHARMACEUTICAL CO LTD (JP)	2021-03-31	—	—	EP	disclosed