SCHEMBL23159587 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	2/20	0.32

▸	CNR2	P34972	9/20	0.31

▸	HTR1A	P08908	1/20	0.31

▸	HTR2C	P28335	1/20	0.31

▸	TP53	P04637	1/20	0.31

▸	SMN1; SMN2	Q16637	1/20	0.31

▸	L3MBTL1	Q9Y468	1/20	0.31

▸	LMNA	P02545	1/20	0.30

▸	KCNH2	Q12809	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23159584	0.83	TSHR (0.33)	TSHRHTR1AHTR2CTP53SMN1; SMN2
SCHEMBL21307302	0.78	NOTUM (0.42)	TSHRCNR2HTR1AHTR2CTP53
SCHEMBL21295037	0.72	TSHR (0.33)	TSHRCNR2HTR1AHTR2CTP53
SCHEMBL21295057	0.71	TSHR (0.33)	TSHRCNR2HTR1AHTR2CTP53
SCHEMBL21295072	0.68	TSHR (0.48)	TSHRTP53SMN1; SMN2L3MBTL1LMNA
SCHEMBL21295048	0.68	FEN1 (0.36)	TSHRL3MBTL1LMNA
SCHEMBL21295089	0.68	FEN1 (0.36)	TSHRCNR2TP53L3MBTL1LMNA
SCHEMBL22855746	0.64	TSHR (0.36)	TSHRCNR2L3MBTL1LMNA
SCHEMBL21295047	0.64	TSHR (0.49)	TSHRTP53SMN1; SMN2L3MBTL1LMNA
SCHEMBL19610383	0.61	KDM1A (0.40)	LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021057910-A1	PEPTIDYLARGININE DEIMINASE INHIBITOR AND USE THEREOF	南京药捷安康生物科技有限公司	2021-04-01	—	—	WO	disclosed