Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2315968 | 1.00 | TAAR1 (0.62) | TAAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2320615 | 0.83 | CNR2 (0.67) | MEN1KMT2AHPGDPOLBALDH1A1 | |
| SCHEMBL2320622 | 0.83 | CNR2 (0.67) | MEN1KMT2AHPGDPOLBALDH1A1 | |
| SCHEMBL2318219 | 0.82 | MME (0.50) | TAAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2318230 | 0.82 | MME (0.50) | TAAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4881537 | 0.81 | TAAR1 (0.50) | TAAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4884489 | 0.81 | TAAR1 (0.50) | TAAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4881521 | 0.81 | TAAR1 (0.50) | TAAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2318924 | 0.81 | MME (0.58) | TAAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2318931 | 0.81 | MME (0.58) | TAAR1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |