⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13728195 | 0.74 | — | — | |
| SCHEMBL16709567 | 0.74 | — | — | |
| SCHEMBL18109836 | 0.74 | — | — | |
| SCHEMBL18109837 | 0.74 | — | — | |
| SCHEMBL13728598 | 0.74 | — | — | |
| SCHEMBL13037485 | 0.74 | — | — | |
| SCHEMBL18632293 | 0.74 | — | — | |
| SCHEMBL7025326 | 0.74 | — | — | |
| SCHEMBL14892385 | 0.74 | — | — | |
| SCHEMBL980432 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1509 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204407-B1 | PROCESS | GIVAUDAN SA (CH) | 2024-06-19 | — | — | EP | claimed |
| US-11970485-B2 | RET kinase inhibitors | ELI LILLY AND COMPANY (US) | 2024-04-30 | — | — | US | claimed |
| US-11964968-B2 | Compounds useful for inhibiting RET kinase | ELI LILLY AND COMPANY (US) | 2024-04-23 | — | — | US | claimed |
| US-20240116854-A1 | CYCLOPROPYLAMIDE COMPOUNDS AGAINST PARASITES IN FISH | INTERVET INC. (US) | 2024-04-11 | — | — | US | claimed |
| US-20240109984-A1 | Catalysts for Olefin Metathesis, Methods of Preparation, and Processes for the use Thereof | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2024-04-04 | — | — | US | claimed |
| US-20240109866-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2024-04-04 | — | — | US | claimed |
| US-20230399297-A1 | Novel Glutamine Analogs | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2023-12-14 | — | — | US | claimed |
| US-20230312506-A1 | PROCESS | GIVAUDAN SA (CH) | 2023-10-05 | — | — | US | claimed |
| US-20230312544-A1 | COMPOUNDS USEFUL FOR INHIBITING RET KINASE | LOXO ONCOLOGY, INC. | 2023-10-05 | — | — | US | claimed |
| EP-4240738-A1 | PYRAZOLE DERIVATIVES AS RET KINASE INHIBITORS | Eli Lilly and Company (US) | 2023-09-13 | — | — | EP | claimed |
| EP-0144103-A2 | Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-06-12 | — | — | EP | claimed |
| EP-0018793-B1 | PEPTIDES AND PROCESS FOR THEIR PREPARATION | ORTHO PHARMACEUTICAL CORPORATION (US) | 1983-11-09 | — | — | EP | claimed |
| EP-0043219-B1 | IMMUNOREGULATORY DIKETOPIPERAZINE COMPOUNDS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1983-10-05 | — | — | EP | claimed |
| US-4369137-A | N-Protected pentapeptides useful as intermediates in the preparation of thymopoietin pentapeptide | ORTHO PHARMACEUTICAL CORPORATION (US) | 1983-01-18 | — | — | US | claimed |
| US-4331595-A | Immunoregulatory diketopiperazine compounds | ORTHO PHARMACEUTICAL CORPORATION (US) | 1982-05-25 | — | — | US | claimed |
| EP-0043219-A1 | Immunoregulatory diketopiperazine compounds | ORTHO PHARMACEUTICAL CORPORATION (US) | 1982-01-06 | — | — | EP | claimed |
| EP-0042291-A2 | Methods and compositions for preparation of H-Arg-X-Z-Y-Tyr-R | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-12-23 | — | — | EP | claimed |
| US-4298523-A | OLIGOPEPTIDES OF ARGININE, LYSINE, VALINE, SARCOSINE, ASPARTIC OR GLUTAMIC ACID, AND TYROSINE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-11-03 | — | — | US | claimed |
| US-4250086-A | Method and composition for preparation of H-SAR-LYS-SAR-GLN-NH2 | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-02-10 | — | — | US | claimed |
| EP-0018793-A2 | Peptides and process for their preparation | ORTHO PHARMACEUTICAL CORPORATION (US) | 1980-11-12 | — | — | EP | claimed |