Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL23163234 | 0.93 | — | — | |
| Bicarbonate SCHEMBL21618365 | 0.93 | — | — | |
| Bicarbonate SCHEMBL27344653 | 0.93 | — | — | |
| Bicarbonate SCHEMBL23163233 | 0.93 | — | — | |
| Bicarbonate SCHEMBL578795 | 0.93 | — | — | |
| Bicarbonate SCHEMBL28292766 | 0.93 | CA1 (0.83) | — | |
| Bicarbonate SCHEMBL23174995 | 0.93 | — | — | |
| Bicarbonate SCHEMBL21815628 | 0.86 | — | — | |
| Bicarbonate SCHEMBL21526741 | 0.86 | — | — | |
| Bicarbonate SCHEMBL22558174 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12329856-B2 | Crosslinked hyaluronic acid composition with local anesthetics | BIOPOLIMERI S.R.L. (IT) | 2025-06-17 | — | — | US | disclosed |
| EP-4362994-B1 | CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS | BIOPOLIMERI S R L (IT) | 2025-03-12 | — | — | EP | disclosed |
| US-20240293311-A1 | CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS | BIOPOLIMERI S.R.L. (IT) | 2024-09-05 | — | — | US | disclosed |
| EP-4362994-A1 | CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS | Biopolimeri S.r.l. (IT) | 2024-05-08 | — | — | EP | disclosed |
| EP-4038105-B1 | A HYPERBRANCHED POLYGLYCEROL POLYGLYCIDYL ETHER AND ITS USE AS CROSSLINKER FOR POLYSACCHARIDES | BIOPOLIMERI S R L (IT) | 2024-01-10 | — | — | EP | disclosed |
| WO-2023275241-A1 | CROSSLINKED HYALURONIC ACID COMPOSITION WITH LOCAL ANESTHETICS | BIOPOLIMERI S.R.L. (IT) | 2023-01-05 | — | — | WO | disclosed |
| US-20220380329-A1 | A HYPERBRANCHED POLYGLYCEROL POLYGLYCIDYL ETHER AND ITS USE AS CROSSLINKER FOR POLYSACCHARIDES | BIOPOLIMERI S.R.L. (IT) | 2022-12-01 | — | — | US | disclosed |
| EP-4038105-A1 | A HYPERBRANCHED POLYGLYCEROL POLYGLYCIDYL ETHER AND ITS USE AS CROSSLINKER FOR POLYSACCHARIDES | Biopolimeri S.r.l. (IT) | 2022-08-10 | — | — | EP | disclosed |
| WO-2021064006-A1 | A HYPERBRANCHED POLYGLYCEROL POLYGLYCIDYL ETHER AND ITS USE AS CROSSLINKER FOR POLYSACCHARIDES | BIOPOLIMERI S.R.L. (ES) | 2021-04-08 | — | — | WO | disclosed |