Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 1/20 | 0.50 |
| ▸ | TTK | P33981 | 5/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.32 |
| ▸ | GPR39 | O43194 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24701362 | 1.00 | EZH2 (0.50) | EZH2TTKCCNA2CDK2MERTK | |
| SCHEMBL23169498 | 0.91 | EZH2 (0.49) | EZH2TTKCCNA2CDK2MERTK | |
| SCHEMBL23169326 | 0.91 | EZH2 (0.49) | EZH2TTKCCNA2CDK2MERTK | |
| SCHEMBL23169380 | 0.90 | EZH2 (0.49) | EZH2TTKCCNA2CDK2MERTK | |
| SCHEMBL23169566 | 0.89 | EZH2 (0.47) | EZH2TTKCCNA2CDK2CCNT1 | |
| SCHEMBL23169336 | 0.88 | EZH2 (0.55) | EZH2MERTK | |
| SCHEMBL24701190 | 0.87 | EZH2 (0.48) | EZH2 | |
| SCHEMBL23169555 | 0.87 | EZH2 (0.54) | EZH2 | |
| SCHEMBL23169459 | 0.86 | EZH2 (0.53) | EZH2TTKCCNA2CDK2MERTK | |
| SCHEMBL23169570 | 0.86 | EZH2 (0.51) | EZH2MERTKCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021057853-A1 | AZA-QUINOLINE COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2021-04-01 | — | — | WO | disclosed |