SCHEMBL2316985

SCHEMBL2316985

C=CC(=O)OCCC1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.48
ALDH1A1 P00352 4/20 0.48
TP53 P04637 3/20 0.48
HIF1A Q16665 3/20 0.48
CYP3A4 P08684 2/20 0.48
HSD17B10 Q99714 1/20 0.48
HPGD P15428 2/20 0.44
EPHX1 P07099 1/20 0.41
THRB P10828 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
MAPK1 P28482 1/20 0.40
NAAA Q02083 4/20 0.38
ASAH1 Q13510 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26935991 1.00 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL20573546 0.98 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16489120 0.90 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL11921515 0.90 TSHR (0.54) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL10894893 0.89 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29602252 0.88 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDEPHX1
SCHEMBL20573854 0.87 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1050595 0.85 EPHX1 (0.44) HPGDEPHX1SMN1; SMN2NAAAASAH1
SCHEMBL1050593 0.85 EPHX1 (0.44) HPGDEPHX1SMN1; SMN2NAAAASAH1
SCHEMBL14509154 0.84 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12460032-B2 Compositions with high refractive index and Abbe number Johnson & Johnson Surgical Vision, Inc. (US) 2025-11-04 US claimed
CN-119072202-A Surface treatment method for improving photoelectric property of perovskite 上海交通大学 2024-12-03 CN claimed
US-20240218102-A1 COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER Johnson & Johnson Surgical Vision, Inc. 2024-07-04 US claimed
US-11958923-B2 Compositions with high refractive index and abbe number Johnson & Johnson Surgical Vision, Inc. (US) 2024-04-16 US claimed
US-11795252-B2 Compositions with high refractive index and Abbe number Johnson & Johnson Surgical Vision, Inc. (US) 2023-10-24 US claimed
EP-4237882-A1 COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER Johnson & Johnson Surgical Vision, Inc. (US) 2023-09-06 EP claimed
US-20230265230-A1 COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER Johnson & Johnson Surgical Vision, Inc. 2023-08-24 US claimed
US-11667742-B2 Compositions with high refractive index and Abbe number Johnson & Johnson Surgical Vision, Inc. (US) 2023-06-06 US claimed
US-11576998-B2 High refractive index, high Abbe number intraocular lens materials ALCON INC. (CH) 2023-02-14 US claimed
US-20220135720-A1 COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER Johnson & Johnson Surgical Vision, Inc. 2022-05-05 US claimed
WO-2020225686-A1 HIGH REACTIVE INDEX, HIGH ABBE COMPOSITIONS Johnson & Johnson Surgical Vision, Inc. (US) 2020-11-12 WO claimed
US-20200347167-A1 COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER Johnson & Johnson Surgical Vision, Inc. 2020-11-05 US claimed
US-20200292730-A1 HIGH REFRACTIVE INDEX, HIGH ABBE NUMBER INTRAOCULAR LENS MATERIALS ALCON RESEARCH, LTD. 2020-09-17 US claimed
US-10712474-B2 High refractive index, high abbe number intraocular lens materials ALCON INC. (CH) 2020-07-14 US claimed
EP-3634508-A1 HIGH REFRACTIVE INDEX, HIGH ABBE NUMBER INTRAOCULAR LENS MATERIALS ALCON INC. (CH) 2020-04-15 EP claimed
CN-110730673-A High refractive index, high Abbe number intraocular lens materials 爱尔康公司 2020-01-24 CN claimed
US-20190339419-A1 HIGH REFRACTIVE INDEX, HIGH ABBE NUMBER INTRAOCULAR LENS MATERIALS ALCON INC. (CH) 2019-11-07 US claimed
US-10408974-B2 High refractive index, high Abbe number intraocular lens materials NOVARTIS AG (CH) 2019-09-10 US claimed
WO-2018224935-A1 HIGH REFRACTIVE INDEX, HIGH ABBE NUMBER INTRAOCULAR LENS MATERIALS NOVARTIS AG (CH) 2018-12-13 WO claimed
US-20180348404-A1 HIGH REFRACTIVE INDEX, HIGH ABBE NUMBER INTRAOCULAR LENS MATERIALS ALCON INC. (CH) 2018-12-06 US claimed