Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 20/20 | 0.62 |
| ▸ | ICAM1 | P05362 | 20/20 | 0.62 |
| ▸ | ITGAL | P20701 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18867800 | 1.00 | ITGB2 (0.62) | ITGB2ICAM1ITGAL | |
| SCHEMBL4755996 | 0.89 | ITGB2 (0.80) | ITGB2ICAM1ITGAL | |
| SCHEMBL19157974 | 0.85 | ITGB2 (0.62) | ITGB2ICAM1ITGAL | |
| SCHEMBL19157560 | 0.84 | ITGB2 (0.70) | ITGB2ICAM1ITGAL | |
| SCHEMBL13435928 | 0.84 | ITGB2 (0.58) | ITGB2ICAM1ITGAL | |
| SCHEMBL22296835 | 0.82 | ITGB2 (0.63) | ITGB2ICAM1ITGAL | |
| SCHEMBL18867524 | 0.81 | ITGB2 (0.81) | ITGB2ICAM1ITGAL | |
| SCHEMBL10168219 | 0.80 | ITGB2 (0.83) | ITGB2ICAM1ITGAL | |
| SCHEMBL18868105 | 0.79 | ITGB2 (0.61) | ITGB2ICAM1ITGAL | |
| SCHEMBL10129644 | 0.75 | ITGB2 (1.00) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3797775-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | Novartis AG (CH) | 2021-03-31 | — | — | EP | disclosed |