Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 20/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 19/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13821870 | 0.93 | ITGAL (0.46) | ITGALITGB2ICAM1 | |
| SCHEMBL23176446 | 0.92 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL18868588 | 0.91 | ITGAL (0.39) | ITGALITGB2ICAM1 | |
| SCHEMBL17992465 | 0.89 | ITGAL (0.45) | ITGALITGB2ICAM1 | |
| SCHEMBL17992509 | 0.86 | ITGAL (0.44) | ITGALITGB2ICAM1 | |
| SCHEMBL23153573 | 0.86 | ITGAL (0.44) | ITGALITGB2ICAM1 | |
| SCHEMBL17991421 | 0.86 | ITGAL (0.44) | ITGALITGB2ICAM1 | |
| SCHEMBL13894114 | 0.86 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL18868508 | 0.85 | ITGAL (0.46) | ITGALITGB2ICAM1 | |
| SCHEMBL17992440 | 0.85 | ITGAL (0.44) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3797775-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | Novartis AG (CH) | 2021-03-31 | — | — | EP | disclosed |