Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23178366 | 0.86 | GRIN2B (0.67) | GRIN2BGRIN1 | |
| SCHEMBL23178856 | 0.78 | GRIN2B (0.54) | GRIN2BGRIN1 | |
| SCHEMBL3394401 | 0.72 | GRIN2B (0.73) | GRIN2BGRIN1 | |
| SCHEMBL23178364 | 0.71 | GRIN2B (0.81) | GRIN2BGRIN1 | |
| SCHEMBL7884889 | 0.71 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL19213976 | 0.71 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL23178360 | 0.70 | GRIN2B (0.88) | GRIN2BGRIN1 | |
| SCHEMBL3393378 | 0.70 | GRIN2B (0.98) | GRIN2BGRIN1 | |
| SCHEMBL23178332 | 0.70 | GRIN2B (0.81) | GRIN2BGRIN1 | |
| SCHEMBL3393198 | 0.69 | GRIN2B (0.77) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210094920-A1 | NR2B LIGANDS; METHOD OF MAKING; AND USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094920-A1 | NR2B LIGANDS; METHOD OF MAKING; AND USE THEREOF | GRIN3A, GRIN3B, GRIN1 | GRIN2B 4/4885GRIN1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.