Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 9/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16922297 | 0.89 | LIMK1 (0.47) | LIMK1CDK5CDK5R1HTR2CHRH4 | |
| SCHEMBL16922544 | 0.87 | LIMK1 (0.46) | LIMK1CDK5CDK5R1HTR2CHRH4 | |
| SCHEMBL20909406 | 0.86 | LIMK1 (0.40) | LIMK1CDK5CDK5R1HTR2CHRH4 | |
| SCHEMBL25473259 | 0.83 | LIMK1 (0.47) | LIMK1CDK5CDK5R1HTR2CHRH4 | |
| SCHEMBL25473296 | 0.83 | LIMK1 (0.47) | LIMK1CDK5CDK5R1HTR2CHRH4 | |
| SCHEMBL24056358 | 0.83 | LIMK1 (0.47) | LIMK1CDK5CDK5R1HTR2CHRH4 | |
| SCHEMBL25473221 | 0.83 | LIMK1 (0.47) | LIMK1CDK5CDK5R1HTR2CHRH4 | |
| SCHEMBL25473431 | 0.82 | LIMK1 (0.49) | LIMK1CDK5CDK5R1HTR2CHRH4 | |
| SCHEMBL16922360 | 0.82 | LIMK1 (0.51) | LIMK1CDK5CDK5R1HTR2CHRH4 | |
| SCHEMBL16901973 | 0.82 | LIMK1 (0.61) | LIMK1CDK5CDK5R1HTR2CHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10968230-B2 | Spiro-structured compound and organic electronic device comprising same | LG CHEM, LTD. | 2021-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968230-B2 | Spiro-structured compound and organic electronic device comprising same | ESR1, OR10J3, ERG | LIMK1 464/4885CDK5 3499/4885CDK5R1 3965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.