Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FSHR | P23945 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29437383 | 0.88 | STK17B (0.40) | STK17BSTK17AGSK3BDYRK1ADRD2 | |
| SCHEMBL2726115 | 0.88 | STK17B (0.40) | STK17BSTK17AGSK3BDYRK1ADRD2 | |
| SCHEMBL22570052 | 0.87 | STK17B (0.39) | STK17BSTK17AGSK3BDYRK1ADRD2 | |
| SCHEMBL30926288 | 0.87 | STK17B (0.39) | STK17BSTK17AGSK3BDYRK1ADRD2 | |
| SCHEMBL16076738 | 0.87 | STK17B (0.39) | STK17BSTK17AGSK3BDYRK1ADRD2 | |
| SCHEMBL2723654 | 0.87 | STK17B (0.40) | STK17BSTK17AGSK3BDYRK1ADRD2 | |
| SCHEMBL29437388 | 0.87 | STK17B (0.40) | STK17BSTK17AGSK3BDYRK1ADRD2 | |
| SCHEMBL25957164 | 0.86 | STK17B (0.40) | STK17BSTK17AGSK3BDYRK1ADRD2 | |
| SCHEMBL16076736 | 0.84 | STK17B (0.37) | STK17BSTK17AGSK3BDYRK1ADRD2 | |
| SCHEMBL30926497 | 0.84 | STK17B (0.37) | STK17BSTK17AGSK3BDYRK1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10966984-B2 | Transient protection of normal cells during chemotherapy | G1 THERAPEUTICS, INC. (US) | 2021-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10966984-B2 | Transient protection of normal cells during chemotherapy | CDK6, CCNC, MCL1 | STK17B 1245/4885STK17A 1696/4885GSK3B 2114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.