Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.67 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23189124 | 0.86 | HCAR2 (0.65) | HCAR2TACR3 | |
| SCHEMBL5083084 | 0.81 | HCAR2 (1.00) | HCAR2 | |
| SCHEMBL23189200 | 0.80 | HCAR2 (0.78) | HCAR2PARP1 | |
| SCHEMBL15964753 | 0.80 | HCAR2 (0.69) | HCAR2PTGES | |
| SCHEMBL23189233 | 0.76 | HCAR2 (0.52) | HCAR2TACR3 | |
| SCHEMBL23189273 | 0.75 | HCAR2 (0.43) | HCAR2 | |
| SCHEMBL23189249 | 0.74 | HCAR2 (0.70) | HCAR2TACR3 | |
| SCHEMBL23188999 | 0.74 | HCAR2 (0.46) | HCAR2RAB9A | |
| SCHEMBL23189158 | 0.70 | HCAR2 (0.72) | HCAR2TACR3 | |
| SCHEMBL3957160 | 0.68 | HCAR2 (0.59) | HCAR2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508484-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2021-04-07 | — | — | EP | disclosed |