Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3323004 | 1.00 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL3320798 | 1.00 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL3322485 | 0.85 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL3326867 | 0.85 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL3322847 | 0.84 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL3320891 | 0.84 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL3317955 | 0.84 | TRPV1 (0.46) | TRPV1 | |
| Hydrochloric Acid SCHEMBL17708768 | 0.83 | TRPV1 (0.45) | TRPV1 | |
| SCHEMBL15021517 | 0.81 | MAP3K14 (0.47) | TRPV1 | |
| SCHEMBL15022431 | 0.81 | MAP3K14 (0.47) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352726-A1 | TRPV1 ANTAGONISTS | Abbott Laboratories (US) | 2011-08-10 | — | — | EP | disclosed |
| EP-2352727-A1 | TRPV1 ANTAGONISTS | Abbott Laboratories (US) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010045401-A1 | TRPV1 ANTAGONISTS | ABBOTT LABORATORIES (US) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010045402-A1 | TRPV1 ANTAGONISTS | ABBOTT LABORATORIES (US) | 2010-04-22 | — | — | WO | disclosed |