SCHEMBL231914

SCHEMBL231914

N=C(N)c1cccc(N)c1

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRSS1 P07477 10/20 0.95
▸ PRSS3 P35030 7/20 0.95
▸ PRSS2 P07478 6/20 0.95
▸ F2 P00734 4/20 0.95
▸ PLG P00747 2/20 0.95
▸ C1S P09871 2/20 0.59
▸ LOXL2 Q9Y4K0 1/20 0.55
▸ F10 P00742 1/20 0.54
▸ F12 P00748 1/20 0.54
▸ F7 P08709 1/20 0.54
▸ F3 P13726 1/20 0.54
▸ PKM P14618 1/20 0.54
▸ PLAU P00749 2/20 0.52
▸ BLM P54132 1/20 0.52
▸ MASP2 O00187 1/20 0.52
▸ THPO P40225 1/20 0.52
▸ PBRM1 Q86U86 1/20 0.52
▸ NOS1 P29475 1/20 0.52
▸ PLAT P00750 1/20 0.52
▸ KLK1 P06870 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL616601 0.98 PRSS1 (1.00) PRSS1PRSS3PRSS2F2PLG
Hydrochloric Acid SCHEMBL5899967 0.98 PRSS1 (1.00) PRSS1PRSS3PRSS2F2PLG
SCHEMBL15547311 0.85 PRSS1 (0.70) PRSS1PRSS3PRSS2F2PLG
SCHEMBL25744914 0.83 PRSS1 (0.68) PRSS1PRSS3PRSS2F2PLG
Hydrochloric Acid SCHEMBL28555629 0.82 PRSS1 (0.74) PRSS1PRSS3PRSS2F2PLG
Hydrochloric Acid SCHEMBL28253026 0.82 PRSS1 (0.74) PRSS1PRSS3PRSS2F2PLG
Hydrochloric Acid SCHEMBL8207271 0.81 PRSS1 (0.69) PRSS1PRSS3PRSS2F2PLG
SCHEMBL14430274 0.79 F2 (0.63) PRSS1PRSS3PRSS2F2PLG
SCHEMBL31650871 0.76 F2 (0.59) PRSS1PRSS3PRSS2F2PLG
3-Aminobenzamide SCHEMBL16070 0.76 PBRM1 (0.63) PRSS1PRSS3PRSS2F2PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116422109-A Self-extraction layered carbon dioxide trapping system and method 嘉兴市碳捕手科技有限责任公司 2023-07-14 — — CN claimed
US-8318904-B2 Liquid, aqueous pharmaceutical compositions of factor VII polypeptides NOVO NORDISK HEALTH CARE AG (CH) 2012-11-27 — — US claimed
CN-101795665-A Method for regulating hair growth PROCTER & GAMBLE 2010-08-04 — — CN claimed
EP-2164457-A2 METHOD OF REGULATING HAIR GROWTH The Procter and Gamble Company (US) 2010-03-24 — — EP claimed
EP-1638623-B1 MODULAR COATING SYSTEM FOR BIO-MATERIALS LEIBNIZ INST POLYMERFORSCHUNG (DE) 2010-03-10 — — EP claimed
US-20100016782-A1 Method of Regulating Hair Growth PROCTER & GAMBLE COMPANY, THE 2010-01-21 — — US claimed
WO-2009010921-A2 METHOD OF REGULATING HAIR GROWTH THE PROCTER & GAMBLE COMPANY (US) 2009-01-22 — — WO claimed
EP-1638623-A1 MODULAR COATING SYSTEM FOR BIO-MATERIALS Leibniz-Institut für Polymerforschung Dresden e.V. (DE) 2006-03-29 — — EP claimed
WO-2005002640-A1 MODULAR COATING SYSTEM FOR BIO-MATERIALS INSTITUT FÜR POLYMERFORSCHUNG DRESDEN E.V. (DE) 2005-01-13 — — WO claimed
CN-1504580-A Combination comprising thrombin agent and examining agent 希森美康株式会社 2004-06-16 — — CN claimed
EP-1020434-A1 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH Kissei Pharmaceutical Co., Ltd. (JP) 2000-07-19 — — EP claimed
US-5534374-A Migration imaging members XEROX CORPORATION (US) 1996-07-09 — — US claimed
EP-0673781-A1 Recording sheets containing amine salts and quaternary choline halides XEROX CORPORATION (US) 1995-09-27 — — EP claimed
EP-0473502-A1 Washing composition capable of preventing and ameliorating skin irritation SHISEIDO COMPANY LIMITED (JP) 1992-03-04 — — EP claimed
CN-220194438-U Carbon dioxide trapping system with self-extraction layering function 嘉兴市碳捕手科技有限责任公司 2023-12-19 — — CN disclosed
CN-116422109-A Self-extraction layered carbon dioxide trapping system and method 嘉兴市碳捕手科技有限责任公司 2023-07-14 — — CN disclosed
WO-2020249139-A1 POTASSIUM SALT CRYSTAL FORM B OF PHOSPHODIESTERASE TYPE 5 INHIBITOR, AND PREPARATION METHOD AND USE THEREFOR 广州华真医药科技有限公司 2020-12-17 — — WO disclosed
US-4130663-A ANTITHROMBOGENIC, ANTIHYPERTENSIVE MEAD JOHNSON & COMPANY (US) 1978-12-19 — — US disclosed
US-4096183-A Styrylsulfonylamidines MEAD JOHNSON & COMPANY (US) 1978-06-20 — — US disclosed
US-4052455-A ANALGESICS, BLOOD PLATELET AGGREGATION INHIBITORS MEAD JOHNSON & COMPANY (US) 1977-10-04 — — US disclosed
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