Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL361129 | 1.00 | CYP2D6 (0.61) | CYP2D6ALDH1A1CYP3A4TSHRCYP1A2 | |
| SCHEMBL8367865 | 1.00 | CYP2D6 (0.61) | CYP2D6ALDH1A1CYP3A4TSHRCYP1A2 | |
| SCHEMBL8370244 | 1.00 | CYP2D6 (0.61) | CYP2D6ALDH1A1CYP3A4TSHRCYP1A2 | |
| SCHEMBL11107669 | 1.00 | CYP2D6 (0.61) | CYP2D6ALDH1A1CYP3A4TSHRCYP1A2 | |
| SCHEMBL22621292 | 1.00 | CYP2D6 (0.61) | CYP2D6ALDH1A1CYP3A4TSHRCYP1A2 | |
| SCHEMBL24250706 | 1.00 | CYP2D6 (0.61) | CYP2D6ALDH1A1CYP3A4TSHRCYP1A2 | |
| SCHEMBL9060935 | 1.00 | CYP2D6 (0.61) | CYP2D6ALDH1A1CYP3A4TSHRCYP1A2 | |
| SCHEMBL777214 | 0.98 | CYP2D6 (0.63) | CYP2D6ALDH1A1CYP3A4TSHRCYP1A2 | |
| Methyl Alcohol SCHEMBL1553775 | 0.97 | CYP2D6 (0.62) | CYP2D6ALDH1A1CYP3A4TSHRCYP1A2 | |
| SCHEMBL6198029 | 0.95 | CYP2D6 (0.63) | CYP2D6ALDH1A1CYP3A4TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11203612-B2 | Methods of generating nanoarrays and microarrays | NAUTILUS BIOTECHNOLOGY, INC. (US) | 2021-12-21 | — | — | US | disclosed |
| US-20210390705-A1 | METHODS AND SYSTEMS FOR COMPUTATIONAL DECODING OF BIOLOGICAL, CHEMICAL, AND PHYSICAL ENTITIES | NAUTILUS SUBSIDIARY, INC. | 2021-12-16 | — | — | US | disclosed |
| WO-2021252800-A1 | METHODS AND SYSTEMS FOR COMPUTATIONAL DECODING OF BIOLOGICAL, CHEMICAL, AND PHYSICAL ENTITIES | NAUTILUS BIOTECHNOLOGY, INC. (US) | 2021-12-16 | — | — | WO | disclosed |
| US-20210101930-A1 | METHODS OF GENERATING NANOARRAYS AND MICROARRAYS | NAUTILUS BIOTECHNOLOGY, INC. | 2021-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210101930-A1 | METHODS OF GENERATING NANOARRAYS AND MICROARRAYS | NAPA, SSBP1, NASP | CYP2D6 4865/4885ALDH1A1 3935/4885CYP3A4 4873/4885 |
| US-11203612-B2 | Methods of generating nanoarrays and microarrays | NAPA, SSBP1, NASP | CYP2D6 4865/4885ALDH1A1 3935/4885CYP3A4 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.