⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19117531 | 0.66 | — | — | |
| SCHEMBL5486985 | 0.66 | — | — | |
| SCHEMBL14596688 | 0.66 | AKT1 (0.32) | — | |
| SCHEMBL28199911 | 0.63 | — | — | |
| SCHEMBL23192611 | 0.62 | — | — | |
| SCHEMBL19881655 | 0.61 | — | — | |
| SCHEMBL12978511 | 0.59 | CHRM3 (0.34) | — | |
| SCHEMBL16303761 | 0.58 | GSK3B (0.32) | — | |
| SCHEMBL18726539 | 0.57 | — | — | |
| SCHEMBL18258290 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3559009-B1 | COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY | CALITHERA BIOSCIENCES INC (US) | 2021-04-07 | — | — | EP | disclosed |