Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 3/20 | 0.57 |
| ▸ | SYK | P43405 | 16/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.54 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30302303 | 1.00 | MAPK8 (0.57) | MAPK8SYKMAPK9ZAP70KCNH2 | |
| SCHEMBL23196158 | 0.89 | MAPK8 (0.55) | MAPK8SYKMAPK9ZAP70KCNH2 | |
| SCHEMBL14658869 | 0.87 | MAPK8 (0.72) | MAPK8SYKMAPK9ZAP70KCNH2 | |
| SCHEMBL24591376 | 0.84 | SYK (0.61) | MAPK8SYKZAP70KCNH2AURKB | |
| SCHEMBL270227 | 0.82 | EGFR (0.55) | MAPK8SYKMAPK9AURKBEGFR | |
| SCHEMBL4713443 | 0.82 | SYK (0.78) | SYKZAP70KCNH2AURKB | |
| Hydrochloric Acid SCHEMBL4711582 | 0.81 | SYK (0.76) | SYKZAP70KCNH2AURKB | |
| SCHEMBL3174240 | 0.78 | AURKA (0.58) | MAPK8SYKMAPK9ZAP70AURKB | |
| SCHEMBL15161205 | 0.77 | SYK (0.66) | MAPK8SYKMAPK9ZAP70KCNH2 | |
| SCHEMBL14657985 | 0.77 | MAPK8 (0.66) | MAPK8SYKMAPK9ZAP70 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4023642-A1 | JNK INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-07-06 | — | — | EP | disclosed |
| WO-2021063207-A1 | JNK INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 武汉朗来科技发展有限公司 | 2021-04-08 | — | — | WO | disclosed |