SCHEMBL23197863

SCHEMBL23197863

B[C@H]1CC(OCSSC(C)(C)CC(C)(C)CC#C)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.30
POLA1 P09884 1/20 0.30
POLD1 P28340 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24730939 0.88 P2RY2 (0.32) POLBPOLA1POLD1
SCHEMBL24730070 0.85 P2RY2 (0.32) POLBPOLA1POLD1
SCHEMBL23197907 0.85 POLB (0.36) POLBPOLA1POLD1
SCHEMBL21786856 0.85 POLB (0.35) POLBPOLA1POLD1
SCHEMBL23197870 0.81 P2RY2 (0.30) POLBPOLA1POLD1
SCHEMBL24730958 0.81 P2RY2 (0.30) POLBPOLA1POLD1
SCHEMBL21786920 0.80 P2RY2 (0.30) POLBPOLA1POLD1
SCHEMBL24896013 0.80 P2RY2 (0.36) POLBPOLA1POLD1
SCHEMBL18841214 0.80 P2RY2 (0.36) POLBPOLA1POLD1
SCHEMBL26333283 0.80 P2RY2 (0.36) POLBPOLA1POLD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021067970-A1 REVERSIBLE TERMINATORS FOR DNA SEQUENCING AND METHODS OF USING THE SAME CENTRILLION TECHNOLOGIES, INC. (US) 2021-04-08 WO disclosed