Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 18/20 | 0.40 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23198556 | 0.95 | PDCD1 (0.39) | CD274PDCD1 | |
| SCHEMBL24759064 | 0.93 | CD274 (0.40) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL24722490 | 0.92 | PDCD1 (0.41) | CD274PDCD1 | |
| SCHEMBL23199854 | 0.91 | PDCD1 (0.39) | CD274PDCD1 | |
| SCHEMBL23198862 | 0.90 | PDCD1 (0.42) | CD274PDCD1 | |
| SCHEMBL23202743 | 0.88 | PDCD1 (0.47) | CD274PDCD1 | |
| SCHEMBL23198491 | 0.88 | PDCD1 (0.50) | CD274PDCD1 | |
| SCHEMBL23199840 | 0.88 | PDCD1 (0.44) | CD274PDCD1 | |
| SCHEMBL23199052 | 0.86 | PDCD1 (0.42) | CD274PDCD1 | |
| SCHEMBL23202665 | 0.86 | PDCD1 (0.51) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4043461-A1 | COMPOUND AS SMALL MOLECULE INHIBITOR PD-1/PD-L1 AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2022-08-17 | — | — | EP | disclosed |
| WO-2021063404-A1 | COMPOUND AS SMALL MOLECULE INHIBITOR PD-1/PD-L1 AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2021-04-08 | — | — | WO | disclosed |