Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 20/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23202743 | 0.93 | PDCD1 (0.47) | PDCD1CD274 | |
| SCHEMBL24722364 | 0.92 | PDCD1 (0.56) | PDCD1CD274 | |
| SCHEMBL23199757 | 0.92 | PDCD1 (0.59) | PDCD1CD274 | |
| SCHEMBL23198558 | 0.91 | PDCD1 (0.55) | PDCD1CD274 | |
| SCHEMBL24722490 | 0.91 | PDCD1 (0.41) | PDCD1CD274 | |
| SCHEMBL23199840 | 0.91 | PDCD1 (0.44) | PDCD1CD274 | |
| SCHEMBL23198491 | 0.89 | PDCD1 (0.50) | PDCD1CD274 | |
| SCHEMBL23201298 | 0.88 | PDCD1 (0.53) | PDCD1CD274 | |
| SCHEMBL23199119 | 0.88 | PDCD1 (0.51) | PDCD1CD274 | |
| SCHEMBL24759064 | 0.87 | CD274 (0.40) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021063404-A1 | COMPOUND AS SMALL MOLECULE INHIBITOR PD-1/PD-L1 AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2021-04-08 | — | — | WO | disclosed |