Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 17/20 | 0.57 |
| ▸ | MTOR | P42345 | 16/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12684765 | 0.86 | PIK3CA (0.67) | PIK3CAMTORPIK3CGPIK3CDHDAC1 | |
| SCHEMBL20914997 | 0.81 | PIK3CA (0.60) | PIK3CAMTORMEN1KMT2APIK3CG | |
| SCHEMBL13828360 | 0.81 | MEN1 (0.62) | PIK3CAMTORMEN1KMT2APIK3CG | |
| SCHEMBL13828335 | 0.78 | MEN1 (0.62) | PIK3CAMTORMEN1KMT2APDE10A | |
| SCHEMBL19119327 | 0.77 | HRH1 (0.68) | PIK3CAMTORMEN1KMT2APDE10A | |
| SCHEMBL12264971 | 0.77 | MEN1 (0.63) | PIK3CAMEN1KMT2APDE10A | |
| SCHEMBL3987061 | 0.76 | MTOR (0.85) | PIK3CAMTORPIK3CGMAPK14CSNK1G1 | |
| Acetic Acid SCHEMBL27773570 | 0.76 | MTOR (0.74) | PIK3CAMTORPIK3CGMAPK14CSNK1G1 | |
| SCHEMBL13828373 | 0.76 | MEN1 (0.62) | PIK3CAMTORMEN1KMT2APDE10A | |
| SCHEMBL12264967 | 0.76 | KMT2A (0.62) | PIK3CAMEN1KMT2APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802826-A1 | METHODS AND COMPOSITIONS FOR EFFICIENT GENE DELETION | CRISPR Therapeutics AG (CH) | 2021-04-14 | — | — | EP | claimed |