Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 8/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | C1S | P09871 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5901036 | 0.83 | KMT2A (0.66) | ST14F2TPSAB1KLKB1F7 | |
| Acetic Acid SCHEMBL23201172 | 0.80 | ST14 (0.55) | ST14F2TPSAB1KLKB1PRSS1 | |
| SCHEMBL8269694 | 0.78 | HDAC1 (0.56) | ST14F2TPSAB1KLKB1F7 | |
| SCHEMBL8290747 | 0.76 | F7 (0.60) | ST14F2TPSAB1KLKB1F7 | |
| SCHEMBL23201173 | 0.76 | ST14 (0.51) | ST14F2TPSAB1KLKB1F7 | |
| SCHEMBL12348110 | 0.75 | F7 (0.67) | ST14F2F7PRSS1PRSS2 | |
| SCHEMBL12348109 | 0.75 | EPHX2 (0.63) | ST14F2TPSAB1F7F10 | |
| SCHEMBL8494151 | 0.75 | HPN (0.57) | ST14F2TPSAB1KLKB1 | |
| SCHEMBL23486915 | 0.75 | ST14 (0.56) | ST14F2F7MASP2 | |
| SCHEMBL48986 | 0.74 | PRSS1 (0.57) | ST14F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802489-A2 | MASP-2 INHIBITORS AND METHODS OF USE | Omeros Corporation (US) | 2021-04-14 | — | — | EP | disclosed |