Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 5/20 | 0.53 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 5/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MASP2 | O00187 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29880438 | 1.00 | HDAC2 (0.53) | HDAC2DPP4RPS6KB1F2KDM1A | |
| SCHEMBL30918644 | 0.91 | HDAC2 (0.61) | HDAC2DPP4RPS6KB1F2MASP2 | |
| SCHEMBL29062785 | 0.91 | HDAC2 (0.61) | HDAC2DPP4RPS6KB1F2MASP2 | |
| Hydrochloric Acid SCHEMBL30471716 | 0.90 | HDAC2 (0.60) | HDAC2DPP4RPS6KB1F2MASP2 | |
| Hydrochloric Acid SCHEMBL30530772 | 0.90 | HDAC2 (0.60) | HDAC2DPP4RPS6KB1F2MASP2 | |
| Trifluoroacetic Acid SCHEMBL17675161 | 0.88 | HDAC2 (0.56) | HDAC2DPP4RPS6KB1KDM1A | |
| Trifluoroacetic Acid SCHEMBL17647118 | 0.88 | HDAC2 (0.56) | HDAC2DPP4RPS6KB1KDM1A | |
| Trifluoroacetic Acid SCHEMBL29796291 | 0.86 | SLC6A2 (0.52) | HDAC2DPP4F2KDM1AMASP2 | |
| Trifluoroacetic Acid SCHEMBL29796286 | 0.86 | SLC6A2 (0.52) | HDAC2DPP4F2KDM1AMASP2 | |
| SCHEMBL30471640 | 0.81 | HTR2C (0.44) | HDAC2DPP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350433-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-112867706-B | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118373875-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-117964684-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117964683-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-115103709-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2022-09-23 | — | — | CN | disclosed |
| EP-3802489-A2 | MASP-2 INHIBITORS AND METHODS OF USE | Omeros Corporation (US) | 2021-04-14 | — | — | EP | disclosed |