Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 2/20 | 0.70 |
| ▸ | HTR5A | P47898 | 1/20 | 0.70 |
| ▸ | HTR2B | P41595 | 17/20 | 0.56 |
| ▸ | HTR2C | P28335 | 16/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.56 |
| ▸ | TMIGD3 | P0DMS9 | 8/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | TSPO | P30536 | 3/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31350147 | 0.87 | HTR2B (0.70) | HRH2HTR5AHTR2BHTR2CADORA1 | |
| SCHEMBL31350186 | 0.86 | HTR2B (0.72) | HRH2HTR5AHTR2BHTR2CADORA1 | |
| SCHEMBL31350070 | 0.85 | HTR2B (0.71) | HRH2HTR5AHTR2BHTR2CADORA1 | |
| SCHEMBL31350256 | 0.84 | HTR2B (0.71) | HRH2HTR5AHTR2BHTR2CADORA1 | |
| SCHEMBL31350105 | 0.84 | HTR2B (0.71) | HRH2HTR5AHTR2BHTR2CADORA1 | |
| SCHEMBL31350145 | 0.84 | HTR2B (0.72) | HRH2HTR5AHTR2BHTR2CADORA1 | |
| SCHEMBL31350257 | 0.83 | HTR2B (0.71) | HRH2HTR5AHTR2BHTR2CADORA1 | |
| SCHEMBL31350228 | 0.83 | HTR2B (0.72) | HRH2HTR5AHTR2BHTR2CADORA1 | |
| SCHEMBL31350117 | 0.83 | HTR2B (0.73) | HRH2HTR5AHTR2BHTR2CADORA1 | |
| SCHEMBL31350104 | 0.82 | HRH2 (0.66) | HRH2HTR5AHTR2BHTR2CADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3801537-A2 | COMPOUNDS AND METHODS FOR MODULATION OF G-PROTEIN-COUPLED RECEPTORS | Primetime Life Sciences, LLC (US) | 2021-04-14 | — | — | EP | disclosed |