Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 4/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2359698 | 0.78 | KDM1A (0.46) | HTR2AHTR2CHTR2BKDM1AABCC9 | |
| SCHEMBL2326665 | 0.77 | SLC6A2 (0.42) | SLC6A2SLC6A3KCNH2SLC6A4HTR2A | |
| SCHEMBL2320349 | 0.75 | SLC6A2 (0.41) | SLC6A2SLC6A3KCNH2SLC6A4CYP2D6 | |
| SCHEMBL2360387 | 0.74 | KDM1A (0.52) | SLC6A2SLC6A3SLC6A4HTR2AHTR2C | |
| SCHEMBL24737999 | 0.72 | FFAR1 (0.49) | IDO1 | |
| SCHEMBL29879365 | 0.72 | FFAR1 (0.49) | IDO1 | |
| SCHEMBL25005218 | 0.70 | KCNH2 (0.40) | SLC6A2SLC6A3KCNH2SLC6A4CYP2D6 | |
| SCHEMBL23995530 | 0.70 | HTR2A (0.49) | SLC6A2SLC6A3KCNH2SLC6A4CYP2D6 | |
| SCHEMBL3147823 | 0.69 | KDM1A (0.44) | SLC6A2SLC6A3KCNH2SLC6A4CYP2D6 | |
| SCHEMBL15517647 | 0.69 | SLC6A2 (0.56) | SLC6A2SLC6A3KCNH2SLC6A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |