Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 7/20 | 0.92 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.92 |
| ▸ | SRC | P12931 | 2/20 | 0.92 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.92 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.92 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.92 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.92 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.92 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.92 |
| ▸ | LDHA | P00338 | 1/20 | 0.92 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.92 |
| ▸ | FBP1 | P09467 | 1/20 | 0.92 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.92 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.92 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.92 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.92 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.92 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.92 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.92 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.92 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine Diphosphate SCHEMBL8359195 | 0.98 | P2RY1 (0.89) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Triphosphate SCHEMBL27817941 | 0.97 | P2RY1 (0.91) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Phosphate SCHEMBL4620813 | 0.97 | P2RY1 (0.94) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Triphosphate SCHEMBL28223308 | 0.96 | P2RY1 (0.89) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Diphosphate SCHEMBL12789537 | 0.96 | P2RY1 (0.92) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Diphosphate SCHEMBL24103 | 0.96 | P2RY1 (0.92) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Diphosphate SCHEMBL195251 | 0.96 | P2RY1 (0.92) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Diphosphate SCHEMBL135142 | 0.96 | P2RY1 (0.92) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Diphosphate SCHEMBL14613190 | 0.96 | P2RY1 (0.92) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 | |
| Adenosine Diphosphate SCHEMBL14180716 | 0.96 | P2RY1 (0.92) | P2RY1P2RY2SRCSMN1; SMN2TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104761507-B | Amido quinazoline derivatives and its application in drug | 广东东阳光药业有限公司 | 2019-11-12 | — | — | CN | disclosed |
| CN-104744446-B | Heteroaryl compound and its application in drug | 广东东阳光药业有限公司 | 2019-06-25 | — | — | CN | disclosed |
| CN-107873028-A | Polycyclic amide derivatives useful as CDK9 inhibitors | 阿斯利康(瑞典)有限公司 | 2018-04-03 | — | — | CN | disclosed |
| CN-104119350-B | Amino quinazoline derivatives as well as salts and application method thereof | 广东东阳光药业有限公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-105399756-A | BTK inhibitor and uses thereof | GUANGDONG HEC PHARMACEUTICAL | 2016-03-16 | — | — | CN | disclosed |
| CN-105294737-A | Compound of CDK small-molecule inhibitor and application thereof | GUANGDONG HEC PHARMACEUTICAL | 2016-02-03 | — | — | CN | disclosed |
| CN-105294683-A | CDK small-molecule inhibitor compounds and application thereof | GUANGDONG HEC PHARMACEUTICAL | 2016-02-03 | — | — | CN | disclosed |
| CN-105294681-A | CDK small-molecule inhibitor compounds and application therefore | GUANGDONG HEC PHARMACEUTICAL | 2016-02-03 | — | — | CN | disclosed |
| CN-105294655-A | CDK small-molecule inhibitor compounds and application therefore | GUANGDONG HEC PHARMACEUTICAL | 2016-02-03 | — | — | CN | disclosed |
| CN-105294736-A | Compound of CDK small-molecule inhibitor and application thereof | GUANGDONG HEC PHARMACEUTICAL | 2016-02-03 | — | — | CN | disclosed |
| CN-105272930-A | Substituted urea derivatives and uses thereof in pharmaceuticals | GUANGDONG HEC PHARMACEUTICAL | 2016-01-27 | — | — | CN | disclosed |
| CN-105153154-A | BTK (bruton tyrosine kinase) inhibitor and purpose of BTK inhibitor | GUANGDONG HEC PHARMACEUTICAL | 2015-12-16 | — | — | CN | disclosed |
| CN-104761507-A | Aminoquinazoline derivatives and use thereof in drugs | GUANGDONG HEC PHARMACEUTICAL | 2015-07-08 | — | — | CN | disclosed |
| CN-104744446-A | Hetero-aromatic compound and application thereof in medicine | GUANGDONG HEC PHARMACEUTICAL | 2015-07-01 | — | — | CN | disclosed |
| CN-104513258-A | Substituted urea derivatives and application thereof in drugs | GUANGDONG HEC PHARMACEUTICAL | 2015-04-15 | — | — | CN | disclosed |
| CN-104513257-A | Substituted urea derivatives and application thereof in drugs | GUANGDONG HEC PHARMACEUTICAL | 2015-04-15 | — | — | CN | disclosed |
| CN-104513259-A | Substituted urea derivatives and application thereof in drugs | GUANGDONG HEC PHARMACEUTICAL | 2015-04-15 | — | — | CN | disclosed |
| CN-104513252-A | Substituted urea derivatives and application thereof in drugs | GUANGDONG HEC PHARMACEUTICAL | 2015-04-15 | — | — | CN | disclosed |
| CN-104119350-A | Amino quinazoline derivatives as well as salts and application method thereof | GUANGDONG HEC PHARMACEUTICAL | 2014-10-29 | — | — | CN | disclosed |
| WO-2011093509-A1 | POLYNUCLEOTIDE ENCODING ACYL-COA SYNTHETASE HOMOLOG AND METHOD FOR USING THE SAME | サントリーホールディングス株式会社 (JP) | 2011-08-04 | — | — | WO | disclosed |