Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 9/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23210301 | 0.82 | CHRM4 (0.47) | CHRM4CHRM1CHRM2CHRM5SLC2A1 | |
| SCHEMBL23210299 | 0.82 | CHRM4 (0.47) | CHRM4CHRM1CHRM2CHRM5SLC2A1 | |
| SCHEMBL23209986 | 0.79 | CHRM4 (0.47) | CHRM4CHRM1CHRM2CHRM5SLC2A1 | |
| SCHEMBL23209984 | 0.79 | CHRM4 (0.47) | CHRM4CHRM1CHRM2CHRM5SLC2A1 | |
| SCHEMBL23210039 | 0.78 | CHRM4 (0.45) | CHRM4CHRM1CHRM2CHRM5OPRL1 | |
| SCHEMBL29843914 | 0.78 | CHRM4 (0.45) | CHRM4CHRM1CHRM2CHRM5OPRL1 | |
| SCHEMBL23210043 | 0.78 | CHRM4 (0.45) | CHRM4CHRM1CHRM2CHRM5OPRL1 | |
| SCHEMBL23209832 | 0.77 | CHRM4 (0.61) | CHRM4CHRM1CHRM2CHRM5 | |
| SCHEMBL23209831 | 0.77 | CHRM4 (0.61) | CHRM4CHRM1CHRM2CHRM5 | |
| SCHEMBL29691248 | 0.77 | CHRM4 (0.61) | CHRM4CHRM1CHRM2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021070090-A1 | 2-AZASPIRO[3.4]OCTANE DERIVATIVES AS M4 AGONISTS | NOVARTIS AG (CH) | 2021-04-15 | — | — | WO | disclosed |