Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23212981 | 0.92 | CHRM4 (0.51) | CHRM4CHRM1CHRM2CHRM5 | |
| SCHEMBL23329060 | 0.92 | CHRM4 (0.51) | CHRM4CHRM1CHRM2CHRM5 | |
| SCHEMBL29619506 | 0.92 | CHRM4 (0.51) | CHRM4CHRM1CHRM2CHRM5 | |
| SCHEMBL23212985 | 0.92 | CHRM4 (0.51) | CHRM4CHRM1CHRM2CHRM5 | |
| SCHEMBL23329061 | 0.92 | CHRM4 (0.51) | CHRM4CHRM1CHRM2CHRM5 | |
| SCHEMBL23212965 | 0.87 | CHRM4 (0.50) | CHRM4CHRM1CHRM2CHRM5 | |
| SCHEMBL23230099 | 0.87 | CHRM4 (0.50) | CHRM4CHRM1CHRM2CHRM5 | |
| SCHEMBL23212963 | 0.87 | CHRM4 (0.50) | CHRM4CHRM1CHRM2CHRM5 | |
| SCHEMBL23230098 | 0.87 | CHRM4 (0.50) | CHRM4CHRM1CHRM2CHRM5 | |
| SCHEMBL29619522 | 0.87 | CHRM4 (0.50) | CHRM4CHRM1CHRM2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021070091-A1 | 5-OXA-2-AZASPIRO[3.4]OCTANE DERIVATIVES AS M4 AGONISTS | NOVARTIS AG (CH) | 2021-04-15 | — | — | WO | disclosed |